Bipolar relationships

Genetic relationships between schizophrenia, bipolar disorder, and schizoaffective disorder.

There is substantial evidence for partial overlap of genetic influences on schizophrenia and bipolar disorder, with family, twin, and adoption studies showing a genetic correlation between the disorders of around 0.6. Results of genome-wide association studies are consistent with commonly occurring genetic risk variants, contributing to both the shared and nonshared aspects, while studies of la...

Bipolar general fuzzy automata

In this paper, we define the notion of a bipolar general fuzzy automaton, then we construct some closure operators on the set of states of a bipolar general fuzzy automaton. Also, we construct some topologies on the set of states of a bipolar general fuzzy automaton. Then we obtain some relationships between them.

Self-mutilation and suicide attempts: relationships to bipolar disorder, borderline personality disorder, temperament and character.

OBJECTIVE Self-mutilation has traditionally been associated with borderline personality disorder, and seldom examined separately from suicide attempts. Clinical experience suggests that self-mutilation is common in bipolar disorder. METHODS A family study was conducted on the molecular genetics of depression and personality, in which the proband had been treated for depression. All probands a...

Bipolar Disorder 3 Treatment of bipolar disorder

We review recent developments in the acute and long-term treatment of bipolar disorder and identify promising future routes to therapeutic innovation. Overall, advances in drug treatment remain quite modest. Antipsychotic drugs are effective in the acute treatment of mania; their efficacy in the treatment of depression is variable with the clearest evidence for quetiapine. Despite their widespr...

Bipolar Disorder